Asos is reportedly planning to make 100 redundancies at its London head office, according to The Times.
Marketing roles are said to be the ones at risk, with the effected people said to be in a consultation period already.
The e-tailers slow in sales growth saw Boohoo overtake it in terms of overall market capitalisation last month.
Its shares had plunged by up to 40% in December when it issued a profit warning.